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JoVE Journal Bioengineering
Ordinazione di singole cellule e singola embrioni in 3D confinamento
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Ordinazione di singole cellule e singola embrioni in 3D confinamento: Un nuovo dispositivo per l'alta Screening contenuti

Article DOI: 10.3791/51880-v • 14:22 min • September 18th, 2016
September 18th, 2016 •
1,2, 1,2, 1,2, 1,2
1Laboratory of Cell Physics, Institut de Science et d'Ingénierie Supramoléculaires (ISIS), CNRS and Université de Strasbourg, 2Development and Stem Cells Program, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), CNRS and Université de Strasbourg

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Riportiamo un dispositivo ed un nuovo metodo per studiare le cellule ed embrioni. celle singole sono proprio ordinati in array microcavità. Il loro confinamento 3D è un passo verso ambienti 3D incontrate in condizioni fisiologiche e permette l'orientamento organelli. Controllando la forma delle cellule, questa configurazione riduce al minimo la variabilità riportata nei test standard.

Tags

Bioingegneria microcavità Replica Molding Microfabbricazione alto contenuto di screening 3 dimensioni singole cellule Nucleo Golgi Cytokinetic Ring.
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