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Journal / Bioengineering / הנקבובי הסיליקון microparticles למשלוח…
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Bioengineering

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JoVE Journal Bioengineering
הנקבובי הסיליקון microparticles למשלוח Therapeutics siRNA
High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles
Journal (Bioengineering)
High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles
Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
Journal (Bioengineering)
Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
 
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הנקבובי הסיליקון microparticles למשלוח Therapeutics siRNA

Article DOI: 10.3791/52075-v • 08:31 min • January 15th, 2015
January 15th, 2015 •
*1,2, *1,3, 1, 1,4, 1, 2, 1,5, 1,6
1Department of Nanomedicine, Houston Methodist Research Institute, 2MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-sen University, 3Pediatrics Department of Union Hospital, Huazhong University of Science and Technology, 4CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience & Technology of China, 5Department of Medicine, Weill Cornell Medical College, 6Department of Cell and Developmental Biology, Weill Cornell Medical College
* These authors contributed equally

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משלוח נשאר האתגר המרכזי ליישום הטיפולי של RNA הקטן מפריע (siRNA). פרוטוקול זה כרוך בשימוש בפלטפורמת משלוח siRNA רב תכליתי וביולוגית, בהיקף של ארגינין וmicroparticles סיליקון הנקבובי polyethylenimine מורכב.

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ביו-הנדסה, סיליקון הנקבובי siRNA מערכת Nanodelivery טיפול בסרטן Transfection functionalization Polycation גיליון 95
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