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Journal / Immunology and Infection / Detectie van Humaan leukocytenantigeen Biomarkers …
JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
Detectie van Humaan leukocytenantigeen Biomarkers bij Borstkanker Gebruikmakend-Label gratis biosensortechnologie
Real-time Imaging of Endothelial Cell-cell Junctions During Neutrophil Transmigration Under Physiological Flow
Journal (Immunology and Infection)
Real-time Imaging of Endothelial Cell-cell Junctions During Neutrophil Transmigration Under Physiological Flow
Analyzing the Effects of Stromal Cells on the Recruitment of Leukocytes from Flow
Journal (Immunology and Infection)
Analyzing the Effects of Stromal Cells on the Recruitment of Leukocytes from Flow
 
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Detectie van Humaan leukocytenantigeen Biomarkers bij Borstkanker Gebruikmakend-Label gratis biosensortechnologie

Article DOI: 10.3791/52159-v • 08:27 min • March 24th, 2015
March 24th, 2015 •
1, 1, 1, 1, 1, 2, 2, 2,3, 1
1Experimmune, A Center for Immunotherapeutic Development, Department of Immunotherapeutics and Biotechnology, Texas Tech University Health Sciences Center, 2Resonant Sensors Incorporated, 3University of Texas Arlington

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Intact klasse I HLA / peptide complexen worden vergoten door kankercellen, wat neerkomt op een potentieel relevante kanker biomarker. Met behulp labelvrije sensortechnologie en T-cel receptor nabootsen monoklonale antilichamen, detectie van stal MIF / HLA-A * 02: 01 complexen in MDA-MB-231 cel supernatanten, spiked humaan serum en plasma van een patiënt wordt aangetoond, waardoor de ontwikkeling van een nieuwe kankertherapie diagnostisch platform.

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Immunologie HLA biomarker borstkanker TCRm diagnostische label-free monoklonaal antilichaam
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