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Glutamat og hypoxi som Stress Model for Isoleret perfuseret Vertebrate Retina
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Glutamat og hypoxi som Stress Model for Isoleret perfuseret Vertebrate Retina

Article DOI: 10.3791/52270-v • 07:48 min • March 22nd, 2015
March 22nd, 2015 •
1, 1, 1, 1, 1, 1, 1, 1, 1
1Centre for Ophthalmology, University Eye Hospital Tübingen

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Med denne undersøgelse, indfører vi en standardiseret stress model for den isolerede superfuseret bovine retina til fremtidig præklinisk terapeutisk test. Virkningen af enten hypoksi (ren N2) eller glutamat stress (250 pM glutamat) på retinal funktion repræsenteret ved a- og b-bølge amplituder blev evalueret.

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Medicine glutamat hypoksi retinal toksicitet elektroretinogrammet intraokulær toksicitet overhældt retina
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