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Polyakrylamidgeler for Invadopodia og Trækkraft Analyser på kræftceller
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Polyakrylamidgeler for Invadopodia og Trækkraft Analyser på kræftceller

Article DOI: 10.3791/52343-v • 08:48 min • January 4th, 2015
January 4th, 2015 •
1, 1
1Department of Otolaryngology, Vanderbilt University Medical Center

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Mekanisk stivhed i tumormikromiljøet spiller en afgørende rolle som drivkraft malign adfærd ved at øge invadopodia aktivitet og actomyosin kontraktilitet. Brug polyacrylamidgeler (cloud) kan invadopodia og trækkraft assays anvendes til at undersøge de invasive og kontraktile egenskaber cancerceller i respons til matrix stivhed.

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Medicine invadopodia trækkraft nedbrydning kontraktilitet stivhed polyacrylamid
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