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可注射药物加载超分子凝胶局部导管注入猪心
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
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可注射药物加载超分子凝胶局部导管注入猪心

English

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17,127 Views

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10:28 min

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June 07, 2015

DOI:

10.3791/52450-v

DOI:
10.3791/52450-v

•

10:28 min
June 07, 2015

•

44 Views
, , , , , , ,
1Institute for Complex Molecular Systems, Department of Biomedical Engineering, Laboratory of Chemical Biology,Eindhoven University of Technology, 2Department of Cardiology, Division Heart and Lungs, Interuniversity Cardiology Institute of the Netherlands (ICIN),University Medical Center Utrecht

Summary

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基于脲基嘧啶酮的水凝胶超分子允许完全控制宏观凝胶特性和使用pH值溶胶 - 凝胶开关行为。在这里，我们提出了一个协议，通过直接局部递送相关领域中的猪心脏的导管输送系统制定和注射这种超分子水凝胶。

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Cite this Article

Pape, A. C. H., Bakker, M. H., Tseng, C. C. S., Bastings, M. M. C., Koudstaal, S., Agostoni, P., Chamuleau, S. A. J., Dankers, P. Y. W. An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart. J. Vis. Exp. (100), e52450, doi:10.3791/52450 (2015).

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