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Journal / Bioengineering / Un supramolecolare idrogel iniettabile and…
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Bioengineering

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JoVE Journal Bioengineering
Un supramolecolare idrogel iniettabile and Drug-caricato per catetere iniezione locale nel cuore di maiale
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Un supramolecolare idrogel iniettabile and Drug-caricato per catetere iniezione locale nel cuore di maiale

Article DOI: 10.3791/52450-v • 10:28 min • June 7th, 2015
June 7th, 2015 •
*1, *1, 2, 1, 2, 2, 2, 1
1Institute for Complex Molecular Systems, Department of Biomedical Engineering, Laboratory of Chemical Biology, Eindhoven University of Technology, 2Department of Cardiology, Division Heart and Lungs, Interuniversity Cardiology Institute of the Netherlands (ICIN), University Medical Center Utrecht
* These authors contributed equally

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Hydrogelators supramolecolari basati su ureido-pyrimidinones consentono il pieno controllo delle proprietà macroscopiche di gel e il comportamento di commutazione sol-gel con pH. Qui, vi presentiamo un protocollo per la formulazione e l'iniezione di un hydrogelator tale supramolecolare tramite un sistema di posizionamento del catetere per la consegna locale direttamente in aree rilevanti nel cuore di maiale.

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Bioingegneria emissione 100 polimeri supramolecolari idrogeli iniezione catetere la somministrazione di farmaci pH commutabilità modello suino
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