Chitosan/Interfering RNA Nanoparticle Mediated Gene Silencing in Disease Vector Mosquito Larvae

Xin Zhang; Keshava Mysore; Ellen Flannery; Kristin Michel; David W. Severson; Kun Yan Zhu; Molly Duman-Scheel

doi:10.3791/52523

Journal

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Biology

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A quitosana / RNA de interferência Nanoparticle Mediated silenciamento gênico na Doença Vector Mosquito Larvas

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Chitosan/Interfering RNA Nanoparticle Mediated Gene Silencing in Disease Vector Mosquito Larvae

A quitosana / RNA de interferência Nanoparticle Mediated silenciamento gênico na Doença Vector Mosquito Larvas

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14,205 Views

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08:36 min

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March 25, 2015

DOI:

10.3791/52523-v

DOI:

10.3791/52523-v

•

08:36 min

March 25, 2015

•

18 Views

Xin Zhang*¹, Keshava Mysore*^2,3, Ellen Flannery^3,4, Kristin Michel¹, David W. Severson^3,4, Kun Yan Zhu⁵, Molly Duman-Scheel^2,3,4

¹Division of Biology,Kansas State University, ²Department of Medical and Molecular Genetics,Indiana University School of Medicine, ³Eck Institute for Global Health,University of Notre Dame, ⁴Department of Biological Sciences,University of Notre Dame, ⁵Department of Entomology,Kansas State University

Summary

Aqui, descrevemos um processo para a inibição da função do gene em vectores mosquitos doença através do uso de quitosano / interferindo nanopartículas de RNA que são ingeridos pelas larvas.

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A quitosana / RNA de interferência Nanoparticle Mediated silenciamento gênico na Doença Vector Mosquito Larvas

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Summary

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