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Human Dupuytren de
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Human Dupuytren de

Article DOI: 10.3791/52534-v • 08:59 min • April 18th, 2015
April 18th, 2015 •
1, 2, 3, 4, 4,5, 1,6
1Department of Molecular Cell Biology, Cancer Genomics Centre and Centre for Biomedical Genetics, Leiden University Medical Center, 2Department of Orthopedic Surgery, Academic Medical Center, 3Department of Plastic, Reconstructive and Hand Surgery, Academic Medical Center, 4Department of Orthopedic Surgery, Mayo Clinic, 5Department of Biochemistry and Molecular Biology, Mayo Clinic, 6Department of Dermatology, Leiden University Medical Center

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La maladie de Dupuytren (DD) est une maladie fibroproliférative de la paume de la main. Ici, nous présentons un protocole à la culture spécimens de résection de DD dans un (3D) système de culture tridimensionnelle. Ce système de culture à court terme permet la préservation de la structure 3D et propriétés moléculaires du tissu fibreux.

Tags

Médecine Numéro 98 la fibrose la maladie de Dupuytren TGFß système de culture 3D écran composé la matrice extracellulaire
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