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Developmental Biology

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JoVE Journal Developmental Biology
Genom-dækkende Snapshot af Chromatin Regulators og stater i
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Genom-dækkende Snapshot af Chromatin Regulators og stater i

Article DOI: 10.3791/52535-v • 10:23 min • February 26th, 2015
February 26th, 2015 •
1, 1, 1
1Division of Systems Biology, MRC National Institute for Medical Research

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Spørgsmålet om, hvordan kromatin tilsynsmyndigheder og kromatin stater påvirker genomet in vivo er nøglen til vores forståelse af, hvordan tidlig celle skæbne beslutninger træffes i det udviklende foster. Chip Seq-den mest populære metode til at undersøge kromatin funktioner på globalt plan-er skitseret her Xenopus embryoner.

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Developmental Biology Chromatin immunopræcipitation næste generation sekventering chip- Seq udviklingsmæssige biologi, cross-linking transskription faktor post-sekventering analyse DNA belægningsprocent metagene bindende motiv GO sigt
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