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Contrast Enhanced Ultrasound Imaging for Assessment of Spinal Cord Blood Flow in Experimental Spinal Cord Injury

Article DOI: 10.3791/52536-v • 09:19 min • May 7th, 2015
May 7th, 2015 •
1,2, 1, 3, 1,4, 1, 2, 1,2
1Laboratoire d'étude de la microcirculation, Faculté de Médecine Paris Diderot Paris VII, U942, 2Department of orthopaedic surgery, Bicetre Universitary Hospital, Public Assistance of Paris Hospital, 3Institute of Medical Science, Faculty of Medicine, University of Toronto, 4Department of Intensive care and Anesthesiology, Bicetre Universitary Hospital, Public Assistance of Paris Hospital

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Summary
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Contrast Enhanced Ultrasound imaging is a reliable in-vivo tool for quantifying spinal cord blood flow in an experimental rat spinal cord injury model. This paper contains a comprehensive protocol for application of this technique in association with a contusion model of thoracic spinal cord injury.

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Contrast Enhanced Ultrasound Imaging Spinal Cord Blood Flow Experimental Spinal Cord Injury Ischemia Neuroprotective Therapies Real-time Imaging Sodium Chloride Solution Sulphur Hexafluoride Encapsulated Microbubbles Jugular Catheter Laminectomy Baseline SCBF Microvasculature Weight-drop Device Post-SCI SCBF Changes In-vivo Assessment
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