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JoVE Journal
Bioengineering

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Concentric Gel System to Study the Biophysical Role of Matrix Microenvironment on 3D Cell Migration
 
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Concentric Gel System to Study the Biophysical Role of Matrix Microenvironment on 3D Cell Migration

Article doi: 10.3791/52735
April 3rd, 2015

Summary April 3rd, 2015

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The mechanical properties and microstructure of the extracellular matrix strongly affect 3D migration of cells. An in vitro method to study the spatiotemporal cell migration behavior in biophysically variable environments, at both population and individual cell levels, is described.

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