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Establishment of a Clinically Relevant Ex Vivo Mock Cataract Surgery Model for Investigating Epithelial Wound Repair in a Native Microenvironment

Article DOI: 10.3791/52886-v • 07:53 min • June 5th, 2015
June 5th, 2015 •
1, 1, 1, 1
1Pathology, Anatomy and Cell Biology, Thomas Jefferson University

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Described here is the establishment of a clinically relevant ex vivo mock cataract surgery model that can be used to investigate mechanisms of the injury response of epithelial tissues within their native microenvironment.

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Ex Vivo Mock Cataract Surgery Model Epithelial Wound Repair Native Microenvironment Lens Epithelium Wound Response Culture Model Molecular Mediators Lens Fiber Cells Circular Wound Posterior Lens Capsule Basement Membrane Monolayer Of Lens Epithelial Cells Vimentin-rich Repair
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