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JoVE Journal Medicine
Orthotope implantatie en Perifere Immune Cell Monitoring in het II-45 Syngene Rat Mesothelioom Model
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Orthotope implantatie en Perifere Immune Cell Monitoring in het II-45 Syngene Rat Mesothelioom Model

Article DOI: 10.3791/53019-v • 09:31 min • October 2nd, 2015
October 2nd, 2015 •
1, 1, 2, 1
1Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research, Royal North Shore Hospital, University of Sydney, 2Northern Blood Research Laboratory, Kolling Institute of Medical Research, Royal North Shore Hospital, University of Sydney

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Het genereren van een orthotopic ratmodel van pleura maligne mesothelioom door implantatie van II-45 mesothelioom cellen in de pleurale holte van immuuncompetente ratten gepresenteerd. Een stroom cytometrische methode zeven immuuncelsubklassen in deze dieren analyseren vanuit een 25 gl bloedmonster wordt ook beschreven.

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Geneeskunde syngeen kanker model orthotope immuun cel rat model kanker circulerende immuun profiel
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