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Journal / Medicine / Udførelse Permanent Distal Mellemøsten Cerebral…
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Udførelse Permanent Distal Mellemøsten Cerebral med Common Arteria carotis Okklusion i Aged Rotter at studere Kortikal Iskæmi med vedvarende handicap
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Udførelse Permanent Distal Mellemøsten Cerebral med Common Arteria carotis Okklusion i Aged Rotter at studere Kortikal Iskæmi med vedvarende handicap

Article DOI: 10.3791/53106-v • 09:11 min • February 23rd, 2016
February 23rd, 2016 •
*1,2, *1,2, 3, 1, 4, 4,5,6, 7, 2, 1
1Wolfson Centre for Age-Related Diseases, King's College London, University of London, 2Department of Neuroimaging, James Black Centre, Institute of Psychiatry, King's College London, University of London, 3Institute of Neuroscience and Psychology, Wellcome Surgical Institute, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, 4Research Service, Edward Hines Jr. VA Hospital, 5Neurology Service, Edward Hines Jr. VA Hospital, 6Department of Molecular Pharmacology and Therapeutics, Neuroscience Research Institute, Loyola University Chicago, 7Department of Oncology, The Gray Institute for Radiation, Oncology and Biology, University of Oxford
* These authors contributed equally

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Her præsenterer vi en protokol til at producere permanent distal midterste cerebral arterie okklusion hos ældre hunrotter med samtidig okklusion af carotis arterierne til at generere store kortikale infarkter og vedvarende underskud. Vi viser bekræftelse af læsionens størrelse under anvendelse strukturel MRI ved 24 timer og 8 uger efter slagtilfælde.

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Medicin Distal mellem-cerebral arterieokklusion MCAO slagtilfælde kirurgi hjerneiskæmi ældre rotter vedvarende underskud koagulation prøvestørrelses beregninger
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