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Developmental Biology

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JoVE Journal Developmental Biology
Tredimensjonal Kvantifisering av dendrittutløperne fra Pyramideformet Nevroner Avledet fra menneskeskapte Pluripotent stamceller
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Tredimensjonal Kvantifisering av dendrittutløperne fra Pyramideformet Nevroner Avledet fra menneskeskapte Pluripotent stamceller

Article DOI: 10.3791/53197-v • 10:18 min • October 10th, 2015
October 10th, 2015 •
1,2,3, 4, 1,2,3, 5, 1,2,3, 1,2,3
1Human Genetics and Cognitive Functions, Institut Pasteur, 2CNRS URA 2182 'Genes, synapses and cognition', Institut Pasteur, 3Human Genetics and Cognitive Functions, Université Paris Diderot, Sorbonne Paris Cité, 4Plateforme d' Imagerie Dynamique, Imagopole, CiTech, Institut Pasteur, 5Neuroplasticity and Therapeutics, CECS, I-STEM, AFM, Evry

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Dendrittutløperne av pyramidale nevroner er nettstedene til de fleste eksitatoriske synapser i hjernen hos pattedyr cortex. Denne metoden beskriver en 3D kvantitativ analyse av ryggraden morfologi i menneskelige kortikale pyramide glutamaterge nevroner avledet fra induserte pluripotente stamceller.

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Developmental Biology Human IPSC-avledet nevroner pyramidale nevroner dendrittiske ryggrad modning spine bildebehandling 3D kvantifisering konfokalmikroskopi
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