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Journal / Developmental Biology / Protokoller for Analysere rolle Paneth Cells i…
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Developmental Biology

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JoVE Journal Developmental Biology
Protokoller for Analysere rolle Paneth Cells i Regenerering muse tarmen ved hjelp Conditional
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Protokoller for Analysere rolle Paneth Cells i Regenerering muse tarmen ved hjelp Conditional

Article DOI: 10.3791/53429-v • 07:48 min • November 21st, 2015
November 21st, 2015 •
1, 1, 2, 1
1European Cancer Stem Cell Research Institute, Cardiff University, 2Institut Curie

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Intestinale epitelceller stamceller (ISCS) er blandet med Paneth celler. Disse cellene differensieres avkommet av ISC, som støtter ISCS og gi antibakteriell beskyttelse. Her viser vi hvordan vi brukte transgene betinget musemodeller for å fastslå at Paneth celler spiller en avgjørende rolle i å opprettholde intestinal epitel.

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Developmental Biology tarm Cre-Lox mus stamcelle Paneth celle transgen
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