Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Neuroscience / En roman-strategien kombinere Array-CGH,…
JoVE Journal
Neuroscience

A subscription to JoVE is required to view this content.

JoVE Journal Neuroscience
En roman-strategien kombinere Array-CGH, hele-exome sekvensering og In Utero elektroporation i gnavere for at identificere sygdomsfremkaldende gener for hjernens misdannelser
Acrylic Resin Molding Based Head Fixation Technique in Rodents
Journal (Neuroscience)
Acrylic Resin Molding Based Head Fixation Technique in Rodents
High-Content Screening Differentiation and Maturation Analysis of Fetal and Adult Neural Stem Cell-Derived Oligodendrocyte Precursor Cell Cultures
Journal (Neuroscience)
High-Content Screening Differentiation and Maturation Analysis of Fetal and Adult Neural Stem Cell-Derived Oligodendrocyte Precursor Cell Cultures
 
Click here for the English version

En roman-strategien kombinere Array-CGH, hele-exome sekvensering og In Utero elektroporation i gnavere for at identificere sygdomsfremkaldende gener for hjernens misdannelser

Article DOI: 10.3791/53570-v • 08:22 min • December 1st, 2017
December 1st, 2017 •
*1, *2,3,15, 2,3,4, 5,6,7, 2,3,8, 1, 2,3, 2,3, 2,3,8, 9, 10, 10, 11, 10, 9,12, 2,3, 13, 1,14, 2,3, 2,3
1University of Florence, 2INSERM INMED, 3Aix-Marseille University, 4Plateforme Biologie Moléculaire et Cellulaire INMED, 5Royal Children's Hospital, 6Murdoch Children's Research Institute, 7University of Melbourne, 8Plateforme postgenomique INMED, 9University of Pavia, 10Wellcome Trust Centre for Human Genetics, 11Oxford Radcliffe NHS Trust, 12IRCCS Casimiro Mondino Foundation, 13Research Institute of Molecular Pathology, 14IRCCS Stella Maris, 15Columbia University
* These authors contributed equally

Chapters

Summary
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

Periventricular nodulær heterotopia (PNH) er den mest almindelige form for misdannelser af kortikale udvikling (MCD) i voksenalderen, men dens genetiske grundlag forbliver ukendt i de fleste sporadiske tilfælde. Vi har for nylig udviklet en strategi til at identificere nye kandidat gener for MCDs og direkte bekræfte deres forårsagende rolle in vivo.

Tags

Neurovidenskab spørgsmålet 130 misdannelser af kortikale udvikling array-CGH hele-exome sekventering i utero elektroporation dyremodel RNA-interferens
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter