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Immunology and Infection

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JoVE Journal Immunology and Infection
Imaging CD4 T-cell Interstitial Migration i Inflammerade Dermis
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Imaging CD4 T-cell Interstitial Migration i Inflammerade Dermis

Article DOI: 10.3791/53585-v • 11:28 min • March 25th, 2016
March 25th, 2016 •
1, 1, 1
1David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY

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De mekanismer som styr den interstitiella motilitet av CD4 T-celler vid inflammationsställen är relativt okänd. Vi presenterar en icke-invasiv metod för att visualisera och manipulera in vitro -primed CD4 T-celler i de inflammerade öron dermis, vilket möjliggör studier av dynamiska beteendet hos dessa celler in situ.

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Immunologi Intravital avbildning multifoton mikroskopi CD4 T-celler mus immunologi cellmigration hud dermis inflammation
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