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Immunology and Infection

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JoVE Journal Immunology and Infection
Zebrafisk som en model til at vurdere det teratogene potentiale af Nitrit
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Zebrafisk som en model til at vurdere det teratogene potentiale af Nitrit

Article DOI: 10.3791/53615-v • 07:29 min • February 16th, 2016
February 16th, 2016 •
1, 1, 1, 1, 1
1Department of Biology, Indiana University of Pennsylvania

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Udsættelse for teratogener kan forårsage fosterskader. Zebrafisk er nyttige til bestemmelse af teratogene potentiale af kemikalier. Vi demonstrerer anvendeligheden af ​​zebrafisk ved at udsætte embryoner til forskellige niveauer af nitrit og også på forskellige tidspunkter af eksponering. Vi viser, at nitrit kan være giftige og forårsage alvorlige udviklingsmæssige defekter.

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Immunologi teratogen Nitrat Nitrit Ethanol zebrafisk Embryo
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