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Transport Properties av Ibuprofen Encapsulated i Cyclodextrin Nanosponge Hydrogeler: En Proton HR-MAS NMR spektroskopi Study

Article DOI: 10.3791/53769-v • 10:10 min • August 15th, 2016
August 15th, 2016 •
*1, *1, 1, 1,2, 3, 4, 5, 1
1Department of Chemistry, Materials and Chemical Engineering "G. Natta", Politecnico di Milano, 2Università degli studi e-Campus, 3ICRM, CNR - Consiglio Nazionale delle Ricerche, 4Elettra Sincrotrone Trieste, 5Department of Chemistry, University of Torino
* These authors contributed equally

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Bevegelses regimer ibuprofen innkapslet i -cyklodekstrin nanosponges polymernettverk blir undersøkt ved hjelp av pulset-field-gradient spin-ekko (PGSE) NMR teknikk. Syntese, rensing, medikamentbelastning, gjennomføring av NMR-pulssekvensen og data-analyse for å regne ut den midlere kvadrat forskyvningen av legemiddel ved flere observasjonstider er beskrevet i detalj.

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Bioteknologi Diffusion HR-MAS NMR-spektroskopi biofysikk polymer syntese cyklodekstrinfrie nanosponges narkotika utgivelse transport fenomener.
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