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Methoden om Ontdek Alternatieve Promoter Gebruik en transcriptionele regulatie van Murine Bcrp1
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Methoden om Ontdek Alternatieve Promoter Gebruik en transcriptionele regulatie van Murine Bcrp1

Article DOI: 10.3791/53827-v • 11:02 min • May 27th, 2016
May 27th, 2016 •
1,2, 1,3, 4, 5,6, 7, 1,3,8,9, 1,3,8,9,10,11
1Greenebaum Cancer Center, University of Maryland School of Medicine, 2Pharmaceutical Sciences, University of Maryland School of Pharmacy, 3Baltimore VA Medical Center, 4Membrane Transport and Biopharmaceutics, School of Pharmaceutical Sciences, Kanazawa University, 5Obstetrics, Gynecology and Reproductive Science, University of Pittsburgh, 6Magee Women's Research Institute, 7Obstetrics, Gynecology, Perinatal Research Branch (NICHD), Wayne State University School of Medicine, 8Medicine, University of Maryland School of Medicine, 9Pathology, University of Maryland School of Medicine, 10Pharmacology, University of Maryland School of Medicine, 11Experimental Therapeutics, University of Maryland School of Medicine

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De muizen ABC transporter Bcrp1 (ABCG2) als voorbeeld, in-silico protocollen worden alternatieve promoter gebruik detecteren genen tot expressie gebracht in muizenweefsels en de functionaliteit van de alternatieve promotors geïdentificeerd onder toepassing reporter assays te evalueren.

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Geneeskunde Promotor Bcrp1 alternatieve promotor gebruik E1U muizen testis steroidogenic factor-1
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