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Murine Model of Intestinal Ischemia-reperfusion Injury

Murine Model of Intestinal Ischemia-reperfusion Injury

Article DOI: 10.3791/53881 07:07 min May 11th, 2016
May 11th, 2016



Here we describe the detailed procedure of intestinal ischemia-reperfusion in mice which results in reproducible injury without mortality to encourage the standardization of this technique across the field. This model of intestinal ischemia-reperfusion injury can be utilized to study the cellular and molecular mechanisms of injury and regeneration.



Murine Model Intestinal Ischemia-reperfusion Injury Reproducible Procedure Superior Mesenteric Artery Gastroenterology Immunology Understanding Mechanisms Patella Injury Regeneration Trained Individual Lab Surgical Site Preparation Laparotomy Sterile Non-adherent Pad Saline Moistened Cotton Swabs Clip Application Stressing Forceps Iris Scissors Mesentery Clip Applier Microvascular Vessel Clip
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