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Usando tomografia Micro-computadas para a avaliação do desenvolvimento do tumor e Acompanhamento da resposta ao tratamento em um modelo do rato do cancro do pulmão
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Using Micro-computed Tomography for the Assessment of Tumor Development and Follow-up of Response to Treatment in a Mouse Model of Lung Cancer

Usando tomografia Micro-computadas para a avaliação do desenvolvimento do tumor e Acompanhamento da resposta ao tratamento em um modelo do rato do cancro do pulmão

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10,454 Views

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11:31 min

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May 20, 2016

DOI:

10.3791/53904-v

DOI:
10.3791/53904-v

•

11:31 min
May 20, 2016

•

23 Views
, , , , , ,
1Division of Pulmonary Medicine,Keio University School of Medicine, 2Department of Developmental Biology,Washington University School of Medicine

Summary

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We describe a method for the detection of tumor nodule development in the lungs of an adenocarcinoma mouse model using micro-computed tomography and its use for monitoring changes in nodule size over time and in response to treatment. The accuracy of the assessment was confirmed with end-point histological quantification.

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Cite this Article

Hegab, A. E., Kameyama, N., Kuroda, A., Kagawa, S., Yin, Y., Ornitz, D., Betsuyaku, T. Using Micro-computed Tomography for the Assessment of Tumor Development and Follow-up of Response to Treatment in a Mouse Model of Lung Cancer. J. Vis. Exp. (111), e53904, doi:10.3791/53904 (2016).

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