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In vivo Biosensor Tracks Non-apoptotiske caspase aktivitet i Drosophila
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In vivo Biosensor Tracks Non-apoptotiske caspase aktivitet i Drosophila

Article DOI: 10.3791/53992-v • 13:21 min • November 27th, 2016
November 27th, 2016 •
1, 1, 2, 1
1W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, 2School of Life Sciences, Chinese University of Hong Kong

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For å detektere friske celler i hele dyr som inneholder lave nivåer av kaspase-aktivitet, ble den meget følsomme biosensor betegnet CaspaseTracker generert for Drosophila. Caspase-avhengig biosensor-aktivitet er detektert i langlivede friske celler gjennom de indre organer hos voksne dyr oppdrettet i henhold optimaliserte betingelser i fravær av døds stimuli.

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Molecular Biology caspase biosensor, apoptose ikke-apoptotiske hjerne nerveceller CaspaseTracker
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