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Cancer Research

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JoVE Journal Cancer Research
Hvordan studere basalmembran Stivhet som Biofysikalsk Trigger i prostatakreft og andre aldersrelaterte patologi eller metabolske sykdommer
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Hvordan studere basalmembran Stivhet som Biofysikalsk Trigger i prostatakreft og andre aldersrelaterte patologi eller metabolske sykdommer

Article DOI: 10.3791/54230-v • 13:18 min • September 20th, 2016
September 20th, 2016 •
1, 2, 3, 3, 3, 3, 3, 1, 3, 3
1Departamento de Genética, Facultad de Medicina, Universidad de la República (UDELAR), 2Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, 3School of Biological, Biomedical & Environmental Sciences, University of Hull

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Her forklarer vi en protokoll for modellering av biofysiske mikromiljøet der kryssbinding og økt stivhet i basalmembran (BM) indusert av avanserte glycation sluttprodukter (aldre) har patologisk betydning.

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Cancer Research Medisin Advanced glycation sluttprodukter basalmembran biofysiske belastningsskader celle migrasjon kollagen IV epitelceller ekstracellulære matrise laminin ikke-enzymatisk kryssbindende prostata kreft stivhet
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