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JoVE Journal Bioengineering
Engineering Tredimensionella epitelvävnader Embedded inom extracellulär matrix
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Engineering Tredimensionella epitelvävnader Embedded inom extracellulär matrix

Article DOI: 10.3791/54283-v • 08:49 min • July 10th, 2016
July 10th, 2016 •
1, 1,2
1Chemical and Biological Engineering, Princeton University, 2Molecular Biology, Princeton University

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Detta manuskript beskriver en mjuk litografi-baserad teknik för att modifiera enhetliga matriser av tredimensionella (3D) epitelvävnader med definierad geometri omgivna av extracellulär matrix. Denna metod är mottaglig för ett stort antal olika celltyper och experimentella sammanhang och gör det möjligt för high-throughput screening av identiska replikat.

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Bioteknik Micropatterning biomekanik molekylärbiologi vävnadsteknik vävnadsgeometri förgrening morfogenes
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