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Anjoniska polymerisationen av en amfifila sampolymeren för framställning av segmentsampolymeren Miceller stabiliseras genom π-Tt stapling interaktioner
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Anjoniska polymerisationen av en amfifila sampolymeren för framställning av segmentsampolymeren Miceller stabiliseras genom π-Tt stapling interaktioner

Article DOI: 10.3791/54422-v • 10:53 min • October 10th, 2016
October 10th, 2016 •
1, 1, 1
1Leslie Dan Faculty of Pharmacy, University of Toronto

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De viktigaste stegen av levande anjoniska polymerisationen av fenylglycidyleter (PheGE) på metoxi-polyetylenglykol (MPEG b -PPheGE) beskrivs. De resulterande segmentsampolymer miceller (BCMS) laddades med doxorubicin 14% (vikt-%) och utdragen frisättning av läkemedel under 4 dygn under fysiologiskt relevanta förhållanden erhölls.

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Kemi anjonpolymerisation segmentsampolymer miceller fenylglycidyleter doxorubicin drug delivery π-Tt stapling interaktioner
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