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JoVE Journal
Bioengineering

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Manufacture and Drug Delivery Applications of Silk Nanoparticles
 

Manufacture and Drug Delivery Applications of Silk Nanoparticles

Article DOI: 10.3791/54669 09:03 min October 8th, 2016
October 8th, 2016

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Summary

Nanoparticles are emerging as promising drug delivery systems for a broad range of indications. Here, we describe a simple yet powerful method to manufacture silk nanoparticles using reverse engineered Bombyx mori silk. These silk nanoparticles can be readily loaded with a therapeutic payload and subsequently explored for drug delivery applications.

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Silk Nanoparticles Drug Delivery Nano-precipitation Aqueous Silk Solution Uniform Silk Nanoparticles Stable Silk Nanoparticles Narrow-side Distribution Sodium Carbonate De-gumming Silk Fibers Washed Silk Air-dried Silk Fibers Lithium Bromide Solution
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