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Évaluation Retinal microglial phagocytaire Fonction

Article DOI: 10.3791/54677-v • 07:19 min • October 18th, 2016
October 18th, 2016 •
1, 1, 2, 1, 1,3, 1
1Department of Cell and Molecular Biology, The Scripps Research Institute, 2Department of Chemical Physiology, The Scripps Research Institute, 3The Lowy Medical Research Institute

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phagocytose microgliale est essentiel pour le maintien de l'homéostasie tissulaire et la fonction phagocytaire insuffisante a été impliquée dans la pathologie. Cependant, l' évaluation de la fonction microglies in vivo est techniquement difficile. Nous avons mis au point une technique simple mais robuste pour surveiller et quantifier le potentiel phagocytaire de la microglie dans un cadre physiologique précisément.

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Immunologie numéro 116 phagocytose microglie macrophage de la rétine, cytométrie en flux les cellules myéloïdes
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