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Journal / Immunology and Infection / Yaratma
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Immunology and Infection

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Yaratma

Article DOI: 10.3791/54697-v • 08:48 min • October 25th, 2016
October 25th, 2016 •
1,2, *2, *2, 2, 1,2, 1,2, 2, 2, 1,2, 1,2
1Department of Immunology, University of Toronto, 2Princess Margaret Cancer Centre, University Health Network
* These authors contributed equally

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Bu yazıda, mevcut bir TCR'nin TCRα ya TCRβ eşleştirme periferal T hücresi reseptör repertuvarının tamamlayıcı hemichain ile, ilgi konusu antijen spesifikliğini sahip antijen-spesifik T hücre reseptörleri (TCR'ler) oluşturmak için yeni bir metot açıklamaktadır. De novo oluşturulan TCRler afiniteye değişen antijen spesifikliğini muhafaza eder.

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Immunology Sayı 116 T hücresi antijen sunan hücre T hücre alıcısı hemichain retroviral transdüksiyon antijen özgüllük insan klonlama
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