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JoVE Journal Genetics

在小鼠心脏rAAV9的制备过表达或敲除基因

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Journal (Genetics)

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage

Journal (Genetics)

Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage

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在小鼠心脏rAAV9的制备过表达或敲除基因

Article DOI: 10.3791/54787-v • 11:11 min • December 17th, 2016

December 17th, 2016 •

Jian Ding^1,2, Zhi-Qiang Lin^1,2, Jian-Ming Jiang^3,4, Christine E. Seidman^3,4, Jonathan G. Seidman^3,4, William T. Pu^1,2, Da-Zhi Wang^1,2

¹Department of Cardiology, Boston Children's Hospital, ²Department of Pediatrics, Harvard Medical School, ³Department of Genetics, Harvard Medical School, ⁴Howard Hughes Medical Institute

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遗传学，第118，基因递送，心肌细胞，腺相关病毒，基因表达，基因敲除，皮下注射

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