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JoVE Journal Neuroscience
Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery
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Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery

Article DOI: 10.3791/54804-v • 06:41 min • January 31st, 2017
January 31st, 2017 •
1, 1, 1, 1,2
1Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, 2The Jerzy Kukuczka Academy of Physical Education

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Summary
Automatic Translation

The present protocol describes a mouse microsurgery infusion technique, which effectively delivers substances directly into the brain via the internal carotid artery.

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Mouse Microsurgery Infusion Technique Targeted Substance Delivery CNS Internal Carotid Artery Exogenous Substances Neuroscience Drugs Pathogens Exosomes Minimal Trauma Neuronal Network High Concentrations Isoflurane Anesthesia Induction Chamber Surgical Surface Stereo Microscope Respiratory Rate Whisker Stimulation Toe Pinch Ophthalmic Lubricant Surgical Site Razor 70% Ethanol Chlorhexidine
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