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Journal / Genetics / 히스톤 - miniSOG에서 사용 Optogenetic 무작위 돌연변이…
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JoVE Journal Genetics
히스톤 - miniSOG에서 사용 Optogenetic 무작위 돌연변이 유발
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히스톤 - miniSOG에서 사용 Optogenetic 무작위 돌연변이 유발

Article DOI: 10.3791/54810-v • 04:51 min • November 14th, 2016
November 14th, 2016 •
1, 1,2
1Division of Biological Sciences, Section of Neurobiology, University of California in San Diego and Howard Hughes Medical Institute, 2Department of Cellular and Molecular Medicine, University of California in San Diego School of Medicine and Howard Hughes Medical Institute

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유전자 인코딩 히스톤 - miniSOG는 푸른 빛 의존적으로 게놈 전체의 유전 변이를 유도한다. 이 돌연변이 유발 방법은 빠르고 간단 독성 화학 물질의 자유, 앞으로 유전자 검사 및 유전자 통합에 적합합니다.

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유전학 문제 117 게놈 전체의 무작위 돌연변이 유발 DNA 변형 ROS 히스톤 - miniSOG 유전자 통합 염색체 삭제 앞으로 유전자 검사
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