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JoVE Journal Medicine
3D quantitativa
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3D quantitativa

Article DOI: 10.3791/54868-v • 09:33 min • December 26th, 2016
December 26th, 2016 •
1, 1, 1
1Zilkha Neurogenetic Institute, University of Southern California (USC)

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Desenvolvemos uma metodologia para 3D quantitativa na modelagem silico (q3DISM) de amilóide cerebral-β (Aâ) fagocitose por fagócitos mononucleares em modelos de roedores da doença de Alzheimer. Este método pode ser generalizado para a quantificação de praticamente qualquer evento fagocítica in vivo.

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Medicina Edição 118 q3DISM TgF344-AD rato APP / PS1 rato amiloidose cerebral fagocitose microglia lisossoma fagolisossomo a doença de Alzheimer
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