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Journal / Medicine / 3D quantitative
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JoVE Journal Medicine
3D quantitative
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3D quantitative

Article DOI: 10.3791/54868-v • 09:33 min • December 26th, 2016
December 26th, 2016 •
1, 1, 1
1Zilkha Neurogenetic Institute, University of Southern California (USC)

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Nous avons développé une méthodologie pour la 3D quantitative dans la modélisation de silico (q3DISM) de amyloïde cérébrale-β (Aß) phagocytose par les phagocytes mononucléaires dans des modèles de rongeurs de la maladie d'Alzheimer. Cette méthode peut être généralisée pour la quantification de pratiquement tous les cas de phagocytose in vivo.

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Médecine numéro 118 q3DISM TgF344-AD rat APP / PS1 souris amylose cérébrale la phagocytose la microglie lysosome phagolysosome la maladie d'Alzheimer
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