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kvantitativ 3D
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kvantitativ 3D

Article DOI: 10.3791/54868-v • 09:33 min • December 26th, 2016
December 26th, 2016 •
1, 1, 1
1Zilkha Neurogenetic Institute, University of Southern California (USC)

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Vi utviklet en metodikk for kvantitativ 3D i silico modellering (q3DISM) av cerebral amyloid-β (Ap) fagocytose av mononukleære fagocytter i gnagermodeller av Alzheimers sykdom. Denne fremgangsmåten kan generaliseres for kvantifisering av praktisk talt alle fagocytisk event in vivo.

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Medisin q3DISM TgF344-AD rotte APP / PS1 mus cerebral amyloidose fagocytose microglia lysosome phagolysosome Alzheimers sykdom
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