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Journal / Medicine / Quantitative 3D
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JoVE Journal Medicine
Quantitative 3D
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Quantitative 3D

Article DOI: 10.3791/54868-v • 09:33 min • December 26th, 2016
December 26th, 2016 •
1, 1, 1
1Zilkha Neurogenetic Institute, University of Southern California (USC)

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Wir entwickelten eine Methode für die quantitative 3D in silico - Modellierung (q3DISM) zerebraler Amyloid-β (Aß) Phagozytose durch mononukleäre Phagozyten in Nagetiermodellen der Alzheimer-Krankheit. Dieses Verfahren kann für die Quantifizierung von praktisch jedem phagozytischen Ereignis in vivo verallgemeinert werden.

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Medizin Ausgabe 118 q3DISM TgF344-AD Ratte APP / PS1 Maus zerebraler Amyloidose Phagozytose Mikroglia Lysosom Phagolysosom Alzheimer-Krankheit
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