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Journal / Bioengineering / Transplante de islotes apoiado em andaimes na…
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Bioengineering
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JoVE Journal Bioengineering
Transplante de islotes apoiado em andaimes na almofada de gordura epidídmica de ratos diabéticos
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Transplante de islotes apoiado em andaimes na almofada de gordura epidídmica de ratos diabéticos

Article DOI: 10.3791/54995-v • 11:58 min • July 23rd, 2017
July 23rd, 2017 •
*1, *1, *2, 2, 1
1Department of Biomedical Engineering, Peking University, 2Institute of Molecular Medicine, Peking University
* These authors contributed equally

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Este protocolo demonstra isolamento de manchas murinas e semeadura em um andaime decelularizado. As ilhotas suportadas em andaimes foram transplantadas para a almofada de gordura epididimática de ratos diabéticos induzidos por estreptozotocina (STZ). As ilhotas sobreviveram no local do transplante e revertearam a condição hiperglicêmica.

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Bioengenharia Edição 125 isolamento de islotes andaime transplante almofada de gordura epidídima murino diabetes
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