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Journal / Immunology and Infection / Dextran fare ve insan birincil NK hücreleri…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Dextran fare ve insan birincil NK hücreleri Lentiviral iletim verimliliğini artırır
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Dextran fare ve insan birincil NK hücreleri Lentiviral iletim verimliliğini artırır

Article DOI: 10.3791/55063-v • 08:42 min • January 15th, 2018
January 15th, 2018 •
1, 2, 3, 4, 5, 6, 6, 1,5,6,7
1Laboratory of Molecular Immunology and Immunotherapy, Blood Research Institute, The Blood Center of Wisconsin, 2Vector Core Lab, Blood Research Institute, The Blood Center of Wisconsin, 3Laboratory of Lymphocyte Biology, Blood Research Institute, The Blood Center of Wisconsin, 4Laboratory of Stem Cell Transcriptional Regulation, Blood Research Institute, The Blood Center of Wisconsin, 5Department of Microbiology and Immunology, The Medical College of Wisconsin, 6Department of Pediatrics, The Medical College of Wisconsin, 7Department of Medicine, The Medical College of Wisconsin

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Bu çalışmanın amacı hücrelerdeki birincil doğal öldürücü (NK) başarılı gen iletim için izin teknolojileri formüle etmek oldu. İnsan lentiviral iletim dextran aracılı veya fare birincil NK hücreleri sonuçlarında yüksek gen ifade verimliliği. Bu yöntemi, gen iletim NK hücre genetik manipülasyon büyük ölçüde artıracaktır.

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İmmünoloji sayı: 131 iletim birincil NK hücreleri dextran genetik olarak değiştirilmiş lentivirus immünoterapi
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