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JoVE Journal Cancer Research
En syngen musemodel af metastaserende renalcellecarcinom for Kvantitativ og Longitudinal Vurdering af Prækliniske Terapier
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En syngen musemodel af metastaserende renalcellecarcinom for Kvantitativ og Longitudinal Vurdering af Prækliniske Terapier

Article DOI: 10.3791/55080-v • 06:38 min • April 12th, 2017
April 12th, 2017 •
*1,2, *1,2,3, 4,5, 1,2,3
1Department of Urology, University of Minnesota, 2Masonic Cancer Center, University of Minnesota, 3Microbiology, Immunology, and Cancer Biology Graduate Program, University of Minnesota, 4Department of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, 5Simmons Cancer Institute
* These authors contributed equally

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Gennemførelse af en orthotopisk model af renalcellekarcinom i immunokompetente mus giver investigator en klinisk relevant system, defineret ved tilstedeværelsen af ​​en primær nyretumor og lungemetastaser i det samme dyr. Dette system kan anvendes til præklinisk afprøve forskellige behandlinger in vivo.

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Cancer Research renalcellecarcinom metastase nyre orthotopisk intrarenal luciferase
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