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JoVE Journal Cancer Research
En syngene mus modell av metastatisk nyrecellekarsinom for Kvantitativ og Langsgående vurdering av Prekliniske terapier
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En syngene mus modell av metastatisk nyrecellekarsinom for Kvantitativ og Langsgående vurdering av Prekliniske terapier

Article DOI: 10.3791/55080-v • 06:38 min • April 12th, 2017
April 12th, 2017 •
*1,2, *1,2,3, 4,5, 1,2,3
1Department of Urology, University of Minnesota, 2Masonic Cancer Center, University of Minnesota, 3Microbiology, Immunology, and Cancer Biology Graduate Program, University of Minnesota, 4Department of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, 5Simmons Cancer Institute
* These authors contributed equally

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Gjennomføring av en ortotopisk modell av nyrecellekarsinom i immunokompetente mus gir utprøver en klinisk relevant system definert ved nærværet av en primær nyretumor og lungemetastaser i det samme dyr. Dette systemet kan brukes til å teste preklinisk en rekke behandlinger in vivo.

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