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Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump

Article DOI: 10.3791/55086-v • 06:08 min • March 11th, 2017
March 11th, 2017 •
1,2,3, 1,3, 4, 2, 1,3
1College of Pharmacy, Yonsei University, 2College of Medicine, Yonsei University, 3Yonsei Institute of Pharmaceutical Sciences, 4Polyscientech Co. Ltd

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Summary
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We report a method for drug sorption evaluation using a pump and model drugs (diazepam and tacrolimus). After drug analysis using high-performance liquid chromatography, drug concentrations and sorption levels in the tubes of administration sets are calculated.

Tags

Drug Sorption PVC-based Tubes Non-PVC-based Tubes Administration Sets Infusion Pump Quality Evaluation Injectable Drug Formulations Sorption Evaluation Accessorized Tubes Procedure Labeling Detachable Accessories Razor Cutting Dilution Process Flow Rate Confirmation Syringe Connection Drug Solution Filling
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