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Journal / Genetics / Détection de Copy Number Transformations…
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Genetics

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JoVE Journal Genetics
Détection de Copy Number Transformations Utilisation unique cellule de séquençage
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Détection de Copy Number Transformations Utilisation unique cellule de séquençage

Article DOI: 10.3791/55143-v • 09:45 min • February 17th, 2017
February 17th, 2017 •
1,2,3, 4, 5
1Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, 2Howard Hughes Medical Institute, 3Division of Health Sciences and Technology, Harvard Medical School, 4The Barbara K. Ostrom (1978) Bioinformatics and Computing Facility in the Swanson Biotechnology Center, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 5BioMicro Center, Department of Biology, Massachusetts Institute of Technology

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séquençage cellulaire unique est un outil de plus en plus populaire et accessible pour aborder les changements génomiques à haute résolution. Nous fournissons un protocole qui utilise le séquençage d'une cellule unique pour identifier des altérations du nombre de copies dans des cellules individuelles.

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Genetics numéro 120 le nombre de copies altération aneuploïdie hétérogénéité génomique monocellulaires amplification du génome entier le séquençage du génome entier
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