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Journal / Biology / Lesão por esmagamento aórtico murino: um…
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JoVE Journal Biology
Lesão por esmagamento aórtico murino
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Lesão por esmagamento aórtico murino: um eficiente

Article DOI: 10.3791/55201-v • 06:14 min • June 11th, 2017
June 11th, 2017 •
1,4, 2, 2,3,4, 2,3,4, 1,2,4
1Department of Surgery, Baltimore Veterans Affairs Medical Center, 2Department of Surgery, University of Maryland School of Medicine, 3Department of Physiology, University of Maryland School of Medicine, 4Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine

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Restenosis após procedimentos cardiovasculares (cirurgia de bypass, angioplastia ou stent) é um problema significativo que reduz a durabilidade desses procedimentos. Uma terapia ideal inibiria a proliferação de células musculares lisas (VSMC) enquanto promovia a regeneração do endotélio. Descrevemos um modelo para avaliação simultânea da proliferação de VSMC e função endotelial in vivo.

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Biologia celular edição 124 aorta modelos animais proliferação celular endotélio células musculares lisas vasculares lesões vasculares
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