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JoVE Journal Bioengineering
Modellierung Ovarian Cancer Vielzellige Sphäroid-Verhalten in einer dynamischen 3D-Peritoneal Microdevice
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Modellierung Ovarian Cancer Vielzellige Sphäroid-Verhalten in einer dynamischen 3D-Peritoneal Microdevice

Article DOI: 10.3791/55337-v • 11:34 min • February 18th, 2017
February 18th, 2017 •
*1, *1, *2, 2, 3, 3, 4, 2, 1
1School of Biological Sciences, University of Hong Kong, 2Department of Mechanical Engineering, University of Hong Kong, 3Department of Medicine, University of Hong Kong, 4Department of Biomedical Sciences, Key Laboratory of Biochip Technology, Biotech and Health Centre, Shenzhen Research Institutes of City University of Hong Kong
* These authors contributed equally

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ovarian Tumorprogression in einem physiologisch relevanten Modell, mehrzelligen Sphäroiden wurden in einem Mikroeinrichtung unter simulierten Fluidstrom zu studieren. Diese dynamische 3D-Modell emuliert die intraperitoneale Umgebung mit den zellulären und mechanischen Komponenten, bei denen Ovarialkarzinom Metastasen auftreten.

Tags

Bioengineering Heft 120 Ovarialkrebs Mikrofluidik Schubspannung peritoneale Mesothelzellen mehrzelligen Sphäroiden 3D-Kultur Co-Kultur
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