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Bioluminescence imagerie de la neuro-inflammation chez des souris transgéniques Après périphériques Ensemencement de l'alpha-synucléine Fibrilles
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Bioluminescence imagerie de la neuro-inflammation chez des souris transgéniques Après périphériques Ensemencement de l'alpha-synucléine Fibrilles

Article DOI: 10.3791/55503-v • 09:32 min • April 13th, 2017
April 13th, 2017 •
1, 1, 1, 2, 2, 1
1German Center for Neurodegenerative Diseases (DZNE), 2Centre for Prions and Protein Folding Diseases & Department of Biochemistry, University of Alberta

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Injection périphérique de fibrilles d'alpha-synucléine dans le péritoine ou de la langue de Tg (+/- M83: GFAP -Luc +/-) des souris qui expriment l' alpha-synucléine humaine avec la mutation A53T familiale et la luciférase de luciole, peut induire une neuropathologie, y compris la neuroinflammation , dans leur système nerveux central.

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Neuroscience numéro 122 l'alpha-synucléine l'imagerie par bioluminescence l'inflammation synucléinopathie neuro-invasion la maladie de Parkinson périphérique prion-like prionoid
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