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Journal / Medicine / Turbidimetri on Human vaskede blodplader:…
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JoVE Journal Medicine
Turbidimetri on Human vaskede blodplader
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Turbidimetri on Human vaskede blodplader: Virkningen af ​​Pannexin1-inhibitoren Brilliant Blue FCF på Collagen-induceret aggregering

Article DOI: 10.3791/55525-v • 09:13 min • April 6th, 2017
April 6th, 2017 •
1, 2, 2, 1
1Department of Pathology and Immunology, University of Geneva, 2Division of Angiology and Haemostasis & Geneva Platelet Group, Geneva University Hospitals

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Vi beskriver en enkel fremgangsmåde til isolering af vaskede blodplader fra humant blod efterfulgt af agonist-induceret blodpladeaggregering målinger ved turbidimetri. Som eksempel anvender vi denne metode til undersøgelse af aggregeringsrespons af humane blodplader til collagen efter en præ-inkubation med Pannexin1 kanal inhibitoren Brilliant Blue FCF.

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Medicin Blodpladeaggregering vaskede blodplader collagen turbidimetri Pannexin1 Brilliant Blue FCF
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