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JoVE Journal Cancer Research
In Vitro Imaging et la quantification de l'efficacité de ciblage des médicaments d'Analogues GnRH marqué par fluorescence
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In Vitro Imaging et la quantification de l'efficacité de ciblage des médicaments d'Analogues GnRH marqué par fluorescence

Article DOI: 10.3791/55529-v • 10:36 min • March 21st, 2017
March 21st, 2017 •
1,2, 1, 1, 1, 3, 2
1MTA-SE Pathobiochemistry Research Group, Semmelweis University, 2Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, 3MTA-ELTE Research Group of Peptide Chemistry, Eötvös Loránd University

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Sélectivement marqué fluorescent GnRH-I, -II et -III dérivés sont des outils fiables pour le suivi et la quantification de leur absorption cellulaire. Ce manuscrit présente des expériences pour visualiser, quantifier et comparer l'efficacité d'absorption de ces conjugués de GnRH dans diverses lignées cellulaires.

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Cancer Research N ° 121 la thérapie ciblée le cancer les cellules tumorales conjugué la microscopie confocale la GnRH le FITC FACS CLSM
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