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Journal / Cancer Research / Vier-Farb-Fluoreszenz-Immunhistochemie von…
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JoVE Journal Cancer Research
Vier-Farb-Fluoreszenz-Immunhistochemie von T-Zell-Subpopulationen im Archiv Formalin-fixierte, Paraffin-eingebettete menschliche Oropharynx-Plattenepithelkarzinom-Proben
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Vier-Farb-Fluoreszenz-Immunhistochemie von T-Zell-Subpopulationen im Archiv Formalin-fixierte, Paraffin-eingebettete menschliche Oropharynx-Plattenepithelkarzinom-Proben

Article DOI: 10.3791/55589-v • 07:43 min • July 29th, 2017
July 29th, 2017 •
1, 2, 1,3
1Department of Pathology, Leiden University Medical Center, 2Department of Otorhinolaryngology and Head and Neck Surgery, Erasmus University Medical Center, 3Center for Gynecological Oncology Amsterdam, VU Medical Center

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Multiparameter-Fluoreszenz-Immunhistochemie kann verwendet werden, um die Anzahl, die relative Verteilung und die Lokalisierung von Immunzellpopulationen in der Tumor-Mikroumgebung zu bestimmen. Dieses Manuskript beschreibt die Verwendung dieser Technik zur Analyse von T-Zell-Subpopulationen bei oropharyngealen Krebs.

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Krebsforschung Immunologie Kopf- und Halskrebs Tumormikroumgebung Fluoreszenzmikroskopie T-Zelle Th17-Zelle Treg IL-17
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